Antimicrobial substances No. 1

The main agents used to treat or prevent infectious diseases of various etiologies are called antimicrobial agents.

They represent a large group, drugs that are different in the mechanism of action, which are subdivided depending on the pathogenic pathogens against which they are effective.

Depending on the etiological causative agent of a particular disease (bacteria, viruses, fungi, helminths, protozoa), various drugs are used.

According to their action, agents are divided into two large groups, namely cidni (bactericidal, virucidal, fungicidal) and static (bacteriostatic, virostatic, fungostatic).

The first group kills microbial pathogens, and the second group inhibits their growth and reproduction.

Antimicrobial agents are needed to combat the vast arsenal of microbial agents that humans come into contact with on a daily basis.

Individuals with an active immune system and high individual immunological resistance rarely develop the disease, mainly with a massive invasion of the body, frequent risky sexual contacts with different partners, and the use of non-sterile needles.

Patients with immunodeficiency as a result of severe systemic diseases, malignant neoplasms, long-term immunosuppressive therapy, after transplantation, severe malnutrition or alcoholism are at an extremely high risk of developing an infectious disease even with minimal exposure to pathogenic agents.

Depending on the type of isolated etiological pathogen, certain groups of antimicrobial agents are used.

Some of them are used once (for example, for helminthiasis), while others require long-term use (bacterial infections) or for the rest of their lives (antiretroviral drugs used for HIV or AIDS).

As for the dosage form of individual drugs, it is always preferable to be most comfortable for the patient, depending on the severity of his condition.

So, for example, with mycosis of nails, mainly topical forms are used, such as gel, cream, ointment, varnish.For mild to moderate bacterial infections, oral forms are most convenient, while for severe systemic infections, regardless of the pathogen, the parenteral route of administration is preferable. my site